The PKN3 Polyclonal Antibody (PAC062763) is a valuable tool for researchers studying PKN3, a protein kinase involved in various cellular processes, including cell proliferation, migration, and survival. Raised in rabbits, this antibody has high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the PKN3 protein, allowing for accurate detection and analysis in different cell types.PKN3 has been implicated in cancer progression, making it a promising target for cancer research.
Its role in cell signaling pathways and tumorigenesis highlights its potential as a therapeutic target for cancer treatment. By understanding the function of PKN3, researchers can uncover new insights into cancer biology and potentially develop targeted therapies for this disease.Overall, the PKN3 Polyclonal Antibody is a reliable tool for investigating the biology of PKN3 and its role in cancer development. Its specificity and sensitivity make it an essential component for studies in oncology and cell biology.
Western Blot. Positive WB detected in: Hela whole cell lysate, PC3 whole cell lysate. All lanes: PKN3 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 100 kDa. Observed band size: 100 kDa.
IHC image of PACO62763 diluted at 1:300 and staining in paraffin-embedded human stomach cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of PACO62763 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Contributes to invasiveness in malignant prostate cancer.
