The PKN2 Polyclonal Antibody (CAB18373) is a valuable tool for researchers studying PKN2, a protein kinase involved in various cellular processes such as cell proliferation, differentiation, and survival. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PKN2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and cancer research.PKN2, also known as protein kinase N2, plays a crucial role in regulating signaling pathways that control cell growth and survival.
Dysregulation of PKN2 has been implicated in the development and progression of various diseases, including cancer and neurodegenerative disorders. Understanding the functions and mechanisms of PKN2 is essential for developing targeted therapies that can potentially address these diseases.In conclusion, the PKN2 Polyclonal Antibody (CAB18373) is a reliable tool for researchers investigating the role of PKN2 in cellular processes and disease development. Its specificity and sensitivity make it an invaluable resource for advancing scientific knowledge and potentially identifying new therapeutic targets.
Product Name:
PRK2/PKN2 Rabbit Polyclonal Antibody
SKU:
CAB18373
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human PRK2/PRK2/PKN2 (NP_006247.1).
apical junction complex, centrosome, cytoplasm, cytosol, intermediate filament cytoskeleton, nuclear body, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane
Calculated MW:
112kDa
Observed MW:
140kDa
Enables RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including apical junction assembly; positive regulation of cell cycle; and positive regulation of viral genome replication. Located in several cellular components, including cleavage furrow; cytoskeleton; and midbody.
Purification Method:
Affinity purification
Gene ID:
5586
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using PRK2/PRK2/PKN2 Rabbit pAb (CAB18373) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
