PKM2 PAT1B10AT Monoclonal Antibody [PAT1B10AT] (CPAB0193)
- SKU:
- CPAB0193
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT1B10AT
- Applications:
- WB
- IF
- ELISA
Description
PKM2 PAT1B10AT Monoclonal Antibody [PAT1B10AT] (CPAB0193)
The PKM2 Polyclonal Antibody (CPAB0193) is a valuable tool for researchers studying the PKM2 protein, a key enzyme involved in glycolysis and cellular metabolism. This antibody is produced in rabbits and is highly specific for detecting PKM2 in human samples, making it ideal for use in Western blot applications.PKM2 is a critical regulator of metabolic pathways in cancer cells, playing a crucial role in tumor growth and progression. Understanding the expression and activity of PKM2 is essential for developing targeted therapies for cancer treatment.
The PKM2 Polyclonal Antibody allows for precise detection and analysis of PKM2 levels in various cell types, making it an essential tool for cancer research and drug discovery efforts.Overall, the PKM2 Polyclonal Antibody is a reliable and efficient tool for studying the role of PKM2 in cancer metabolism, providing insight into potential therapeutic targets for cancer treatment.
Product Name: | PKM2 PAT1B10AT Antibody |
Product Sku: | CPAB0193 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PKM2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PKM2 protein 1-531 amino acids purified from Ecoli. |
Clone: | PAT1B10AT. |
Reactivity: | Human |
Applications: | Western Blot, Immunofluorescence, ELISA |
Purification Method: | PKM2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. |
Synonyms: | Pyruvate kinase isozymes M1/M2, EC 2.7.1.40, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, M2PK, PKM2, PK3, PK2, PKM, TCB, OIP3, MGC3932, Tumor Type M2 Pyruvate Kinase. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |