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PKM2 Monoclonal Antibody [PAT1B10AT] (CPAB0096)

SKU:
CPAB0096
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT1B10AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

PKM2 Monoclonal Antibody [PAT1B10AT] (CPAB0096)

The PKM2 Polyclonal Antibody (CPAB0096) is a valuable tool for researchers studying the pyruvate kinase M2 (PKM2) protein, which plays a crucial role in regulating glycolysis and metabolic reprogramming in cancer cells. This antibody, produced in rabbits, has high specificity for PKM2 and has been validated for use in various research applications, including Western blot analysis.PKM2 is a key enzyme involved in tumor metabolism, with its expression levels and activity being linked to cancer progression and aggressiveness. By targeting PKM2, researchers can gain insights into the metabolic alterations that occur in cancer cells, potentially leading to the development of novel therapeutic strategies for cancer treatment.

With its ability to specifically detect PKM2 in various cell types, the PKM2 Polyclonal Antibody is an essential tool for studies exploring the role of metabolism in cancer biology and for identifying potential targets for anti-cancer therapies. Its reliability and versatility make it a valuable asset for researchers in the fields of oncology and molecular biology.

Product Name:PKM2 Antibody
Product Sku:CPAB0096
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PKM2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PKM2 amino acids 1-531 purified from Ecoli.
Clone:PAT1B10AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PKM2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.
Synonyms:Pyruvate kinase isozymes M1/M2, EC 2.7.1.40, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, M2PK, PKM2, PK3, PK2, PKM, TCB, OIP3, MGC3932, Tumor Type M2 Pyruvate Kinase.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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