PKIG Antibody (PACO59972)
- SKU:
- PACO59972
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PKIG Antibody (PACO59972)
The PKIG Polyclonal Antibody (PAC059972) is a valuable tool for researchers studying PKIG, a protein kinase implicated in various cellular processes. This antibody is produced in rabbits and specifically targets human samples, making it an ideal choice for Western blot applications. By binding to the PKIG protein, researchers can effectively detect and analyze PKIG expression in different cell types, making it a versatile tool for studies in cell biology and signal transduction pathways.PKIG, also known as protein kinase inhibitor gamma, plays a crucial role in regulating cell growth, differentiation, and apoptosis. Its involvement in these essential cellular processes makes it a promising target for research in cancer biology, neurobiology, and developmental biology.
By studying the function of PKIG, researchers can gain valuable insights into potential therapeutic strategies for various diseases and disorders related to abnormal cell signaling pathways.Overall, the PKIG Polyclonal Antibody is an essential reagent for researchers looking to explore the role of PKIG in different biological contexts. Its high reactivity, specificity, and reliability make it a valuable tool for advancing our understanding of cellular signaling mechanisms and identifying potential therapeutic targets for a range of diseases.
| Antibody Name: | PKIG Antibody (PACO59972) |
| Antibody SKU: | PACO59972 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human cAMP-dependent protein kinase inhibitor γ protein (1-76AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of PC-3 cells with PACO59972 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. |
| Synonyms: | cAMP-dependent protein kinase inhibitor γ (PKI-gamma), PKIG |
| UniProt Protein Function: | PKIG: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Inhibitor; Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 20q12-q13.1 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity Biological Process: negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; signal transduction |
| NCBI Summary: | This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9Y2B9 |
| NCBI GenInfo Identifier: | 74355324 |
| NCBI Gene ID: | 11142 |
| NCBI Accession: | AAI04257.1 |
| UniProt Related Accession: | Q9Y2B9 |
| Molecular Weight: | 7,910 Da |
| NCBI Full Name: | Protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Synonym Full Names: | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Official Symbol: | PKIGÂ Â |
| NCBI Official Synonym Symbols: | PKI-gamma  |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor gamma |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor gamma |
| Protein Family: | cAMP-dependent protein kinase |
| UniProt Gene Name: | PKIGÂ Â |
| UniProt Entry Name: | IPKG_HUMAN |
| Antibodies | ELISA Kits |
| PKIG Antibody (PACO11270) | Human PKIgamma (Protein Kinase Inhibitor Gamma) ELISA Kit (HUES02267) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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