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PKIB Antibody (PACO11269)

SKU:
PACO11269
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551

Description

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PKIB Antibody (PACO11269)

The PKIB Polyclonal Antibody (PACO11269) is a crucial tool for researchers studying the protein kinase inhibitor beta (PKIB) in various cellular processes. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications. By binding to the PKIB protein, this antibody enables accurate detection and analysis in a wide range of cell types.PKIB is known to play a significant role in regulating intracellular signaling pathways related to cell growth, proliferation, and differentiation. Its involvement in various physiological and pathological processes makes it a valuable target for research in areas such as cancer biology, neuroscience, and cardiovascular disease.

By understanding the function of PKIB, researchers can uncover potential therapeutic targets for treating diseases associated with dysregulated signaling pathways.Overall, the PACO11269 antibody provides researchers with a reliable tool for investigating the role of PKIB in cellular signaling and disease pathogenesis, ultimately contributing to advancements in the fields of molecular biology and medicine.

Antibody Name:PKIB Antibody (PACO11269)
Antibody SKU:PACO11269
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human PKIB
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:protein kinase (cAMP-dependent, catalytic) inhibitor beta;PKIB;FLJ23817;PRKACN2 ;
UniProt Protein Function:PKIB: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.
UniProt Protein Details:

Protein type:Protein kinase, regulatory subunit; Inhibitor

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function:cAMP-dependent protein kinase inhibitor activity

NCBI Summary:This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
UniProt Code:Q9C010
NCBI GenInfo Identifier:17378640
NCBI Gene ID:5570
NCBI Accession:Q9C010.1
UniProt Secondary Accession:Q9C010,Q567T9, Q5T0Z7, B2RCK2,
UniProt Related Accession:Q9C010
Molecular Weight:9,237 Da
NCBI Full Name:cAMP-dependent protein kinase inhibitor beta
NCBI Synonym Full Names:protein kinase (cAMP-dependent, catalytic) inhibitor beta
NCBI Official Symbol:PKIB  
NCBI Official Synonym Symbols:PRKACN2  
NCBI Protein Information:cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2
UniProt Protein Name:cAMP-dependent protein kinase inhibitor beta
Protein Family:cAMP-dependent protein kinase
UniProt Gene Name:PKIB  
UniProt Entry Name:IPKB_HUMAN

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