The PKD2L2 Polyclonal Antibody (PAC041754) is a valuable tool for researchers studying PKD2L2, a protein involved in various cellular processes, including ion channel activity and signal transduction. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications.PKD2L2, also known as polycystic kidney disease 2-like 2 protein, is implicated in the development and function of the kidney, as well as other tissues. Dysregulation of PKD2L2 has been associated with certain kidney disorders and other diseases, making it a promising target for investigations in the fields of nephrology and cell biology.
By utilizing the PKD2L2 Polyclonal Antibody, researchers can effectively detect and analyze the expression of PKD2L2 in various cell types and tissues, providing valuable insights into its biological functions and potential therapeutic implications. This antibody is an essential tool for advancing our understanding of PKD2L2 and its role in health and disease.
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO41754 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO41754 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May function as a subunit of a cation channel and play a role in fertilization.
Synonyms:
Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2), PKD2L2
UniProt Protein Function:
PKD2L2: May function as a subunit of a cation channel and play a role in fertilization. Belongs to the polycystin family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 5q31Cellular Component: integral to membraneMolecular Function: calcium channel activityBiological Process: detection of mechanical stimulus
