UniProt Protein Function: | PKD1L3: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels. Belongs to the polycystin family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 16q22.2Cellular Component: cell surface; plasma membrane; receptor complexMolecular Function: calcium channel activity; cation channel activity; cation transmembrane transporter activity; protein binding; sour taste receptor activityBiological Process: cation transport; detection of chemical stimulus involved in sensory perception of sour taste; detection of mechanical stimulus; sensory perception of sour taste |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009] |
UniProt Code: | Q7Z443 |
NCBI GenInfo Identifier: | 31559825 |
NCBI Gene ID: | 342372 |
NCBI Accession: | NP_853514.1 |
UniProt Secondary Accession: | Q7Z443 |
UniProt Related Accession: | Q7Z443 |
Molecular Weight: | 195,894 Da |
NCBI Full Name: | polycystic kidney disease protein 1-like 3 |
NCBI Synonym Full Names: | polycystin 1 like 3, transient receptor potential channel interacting |
NCBI Official Symbol: | PKD1L3Â Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | polycystic kidney disease protein 1-like 3 |
UniProt Protein Name: | Polycystic kidney disease protein 1-like 3 |
UniProt Synonym Protein Names: | PC1-like 3 protein; Polycystin-1L3 |
Protein Family: | Polycystic kidney disease protein |
UniProt Gene Name: | PKD1L3Â Â |
UniProt Entry Name: | PK1L3_HUMAN |