The PKD1L2 Polyclonal Antibody (CAB14954) is a valuable tool for researchers studying PKD1L2, a protein kinase involved in various cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for Western blot analysis. By selectively binding to PKD1L2, the antibody facilitates accurate detection and analysis of the protein in different cell types, thereby facilitating investigations in the fields of cell biology and cancer research.PKD1L2 is known to play a crucial role in cell signaling pathways and the regulation of gene expression, making it a promising target for the development of therapeutic interventions.
Its involvement in processes such as cell proliferation, differentiation, and survival underscores its importance in various disease states, including cancer and neurological disorders. The PKD1L2 Polyclonal Antibody offers researchers a reliable tool for exploring the functions and mechanisms of this protein, paving the way for potential advancements in the treatment of associated conditions.
Product Name:
PKD1L2 Rabbit Polyclonal Antibody
SKU:
CAB14954
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1).
This gene encodes a member of the polycystin protein family. This protein may function as a G-protein-coupled component or regulator of cation channel pores. The long isoform of this protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene is a polymorphic pseudogene in humans.
Purification Method:
Affinity purification
Gene ID:
114780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using PKD1L2 Rabbit pAb (CAB14954) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
