PKC epsilon Rabbit Monoclonal Antibody (CAB4998)
- SKU:
- CAB4998
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PKCE
- nPKC-epsilon
- Research Area:
- Cell Biology
Description
Product Name: | PKC epsilon Rabbit Monoclonal Antibody |
SKU: | CAB4998 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human PKC epsilon (Q02156). |
Sequence: | RSRK FDEP RSRF YAAE VTSA LMFL HQHG VIYR DLKL DNIL LDAE GHCK LADF GMCK EGIL NGVT TTTF CGTP DYIA PEIL QELE YGPS VDWW ALGV LMYE M |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PKCE; nPKC-epsilon; PKC epsilon |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, Cytoskeleton, Perinuclear region. |
Calculated MW: | 84kDa |
Observed MW: | 82kDa |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
Purification Method: | Affinity purification |
Gene ID: | 5581 |
Clone Number: | ARC1270 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |