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PKC alpha Monoclonal Antibody (CAB23231)

SKU:
CAB23231
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
$167 - $635
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PKC alpha Monoclonal Antibody
SKU:CAB23231
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant protein of human PKC alpha.
Tested Applications:IF/ICC ELISA
Recommended Dilution:IF/ICC,1:50 - 1:200
Synonyms:AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Mitochondrion membrane, Nucleus, Peripheral membrane protein.
Calculated MW:77kDa
Observed MW:Refer to figures

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Purification Method:Affinity purification
Gene ID:5578
Clone Number:ARC58845
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageImmunofluorescence analysis of HeLa cells using PKC alpha Rabbit mAb (CAB23231) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

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