PKC alpha + beta + gamma Monoclonal Antibody (CAB24003)
- SKU:
- CAB24003
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | PKC alpha + beta + gamma Monoclonal Antibody |
SKU: | CAB24003 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-500 of human PKC alpha + beta + gamma (NP_002728.2/NP_002729.2/NP_002730.1). |
Sequence: | ELRQ KFER AKIS QGTK VPEE KTTN TVSK FDNN GNRD RMKL TDFN FLMV LGKG SFGK VMLS ERKG TDEL YAVK ILKK DVVI QDDD VECT MVEK RVLA LPGK PPFL TQLH SCFQ TMDR LYFV MEYV NGGD LMYH IQQV GRFK EPHA VFYA AEIA IGLF FLQS KGII YRDL KLDN VMLD SEGH IKIA DFGM CKEN IWDG VTTK T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha; PKC alpha + beta + gamma |
Positive Sample: | HeLa,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Mitochondrion membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 78kDa |
Observed MW: | 78kDa |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Purification Method: | Affinity purification |
Gene ID: | 5578/ 5579/ 5582/ 5581 |
Clone Number: | ARC3211 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |