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PJVK Monoclonal Antibody

SKU:
CAB23724
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
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Description

PJVK Monoclonal Antibody (CAB23724)

The PJVK Monoclonal Antibody is a specialized antibody designed for research involving PJVK, a protein linked to hearing loss and deafness. This monoclonal antibody, developed using cutting-edge technology, is highly specific and reactive with human samples, making it an ideal tool for various research applications.PJVK, also known as pejvakin, is a key player in the auditory system, playing a vital role in maintaining the health and function of hair cells in the inner ear. Mutations in the PJVK gene have been associated with progressive hearing loss and deafness, making it a target of interest for researchers in the field of otology and auditory science.

This monoclonal antibody enables the detection and analysis of PJVK protein in cell samples, allowing researchers to study its function and role in hearing loss disorders. By understanding the mechanisms of PJVK and its impact on auditory function, researchers can potentially develop new therapies and interventions for individuals affected by hearing loss and deafness.

Product Name:PJVK Monoclonal Antibody
Product Code:CAB23724
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC61181
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:293T-PJVK
Cellular Location:Peroxisome membrane, cilia

The protein encoded by this gene is a member of the gasdermin family, a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59).

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 290-352 of human PJVK（NP_001036167.1）.
Sequence:KEGTH IRVNL LNHNI PKGPC ILCGM GNFKR ETVYG CFQCS VDGQK YVRLH AVPCF DIWHK RMK
Synonyms:DFNB59
Calculated MW:40kDa
Observed MW:45kDa

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