The PIWIL4 Polyclonal Antibody (CAB13201) is a valuable tool for researchers studying PIWIL4, a member of the PIWI protein family involved in RNA silencing and germ cell development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the PIWIL4 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in the fields of molecular biology and reproductive biology.
PIWIL4, also known as PIWI-like protein 4, is essential for maintaining genomic integrity and regulating gene expression by silencing transposable elements and long non-coding RNAs. Its critical role in germ cell development and epigenetic regulation emphasizes its significance in reproductive health and potential implications for infertility and reproductive disorders. Understanding the functions of PIWIL4 is essential for advancing knowledge in these areas and exploring its therapeutic potential in reproductive medicine.
Product Name:
PIWIL4 Rabbit Polyclonal Antibody
SKU:
CAB13201
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-460 of human PIWIL4 (NP_689644.2).
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).
Purification Method:
Affinity purification
Gene ID:
143689
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIWIL4 Rabbit pAb (CAB13201) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.