The Piwi-like protein 2 Polyclonal Antibody (CAB6044) is a valuable tool for researchers studying Piwi-like protein 2, a key player in RNA silencing and germ cell development. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By binding to the Piwi-like protein 2, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies focusing on RNA regulation and reproductive biology.Piwi-like protein 2, a member of the Piwi subfamily, is essential for maintaining genome integrity and germ cell differentiation by suppressing transposable elements and regulating gene expression.
Its crucial role in RNA interference pathways implicates it in a wide range of biological processes, including stem cell maintenance and fertility. Researchers exploring the functions of Piwi-like protein 2 can gain insights into mechanisms underlying genetic stability and developmental processes, with potential implications for reproductive health and cancer research.
Product Name:
PIWIL2 Rabbit Polyclonal Antibody
SKU:
CAB6044
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 398-652 of mouse PIWIL2 (Q8CDG1).
Enables RNA binding activity; endoribonuclease activity; and polysome binding activity. Involved in several processes, including germ-line stem cell population maintenance; nucleic acid metabolic process; and positive regulation of cellular protein metabolic process. Acts upstream of or within oogenesis and positive regulation of meiosis I. Located in several cellular components, including cytoplasmic ribonucleoprotein granule; dense body; and perinucleolar chromocenter. Part of PET complex. Is expressed in central nervous system; genitourinary system; and sensory organ. Orthologous to human PIWIL2 (piwi like RNA-mediated gene silencing 2).
Purification Method:
Affinity purification
Gene ID:
57746
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PIWIL2 antibody (CAB6044) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
