The PITPNB Polyclonal Antibody (PAC011262) is a valuable tool for researchers studying PITPNB, a protein involved in phosphatidylinositol and phosphatidylcholine biosynthesis. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting PITPNB in human samples, making it suitable for use in Western blot applications. By binding to the PITPNB protein, this antibody allows for accurate analysis and investigation of PITPNB expression in various cell types, making it an essential component for studies in cell biology and lipid metabolism.PITPNB, also known as phosphatidylinositol transfer protein beta, plays a crucial role in lipid metabolism and intracellular signaling pathways. Its involvement in lipid transport and lipid-mediated signaling processes makes it a key player in cellular homeostasis and membrane trafficking.
Research on PITPNB is instrumental in understanding its impact on various cellular functions and its potential implications in diseases related to lipid metabolism and signaling dysregulation.By utilizing the PITPNB Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of PITPNB, paving the way for advancements in drug development and targeted therapies for diseases associated with lipid metabolism abnormalities. Make the PITPNB Polyclonal Antibody a part of your research toolkit to unravel the mysteries of lipid biology and its implications for human health and disease.
phosphatidylinositol transfer protein, beta;PITPNB;PI-TP-beta;PtdInsTP;VIB1B ;
UniProt Protein Function:
PITPNB: transfers phosphatidylinositol, phosphatidylcholine and sphingomyelin between membrane bilayers. Associates mainly with the trans-Golgi network. Ser-261 is constitutively phosphorylated.Protein type: Lipid-bindingChromosomal Location of Human Ortholog: 22q12.1Cellular Component: endoplasmic reticulum membrane; Golgi membraneBiological Process: phospholipid transport
UniProt Protein Details:
NCBI Summary:
This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
