The PITPNA Polyclonal Antibody (CAB12966) is a valuable tool for researchers studying PITPNA, a key protein involved in lipid metabolism and intracellular signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting. By binding specifically to PITPNA, this antibody enables precise detection and analysis of the protein in different cell types, making it ideal for studies in cell biology, lipid signaling, and membrane trafficking.PITPNA, also known as phosphatidylinositol transfer protein alpha, is crucial for the transport of phosphatidylinositol, a key component of cell membranes, and is involved in regulating important cellular processes such as signal transduction and vesicular trafficking.
Dysregulation of PITPNA has been linked to various human diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By investigating the functions of PITPNA, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new treatment strategies.
Product Name:
PITPNA Rabbit Polyclonal Antibody
SKU:
CAB12966
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 211-270 of human PITPNA (NP_006215.1).
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
Purification Method:
Affinity purification
Gene ID:
5306
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PITPNA Rabbit pAb (CAB12966) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
