The PIP5K1B Polyclonal Antibody (CAB7749) is a valuable tool for researchers studying the PIP5K1B protein, which plays a crucial role in cellular signaling pathways related to lipid metabolism and membrane dynamics. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blotting applications.PIP5K1B, also known as phosphatidylinositol 4-phosphate 5-kinase type 1 beta, is involved in the production of phosphatidylinositol 4,5-bisphosphate (PIP2), which is a key regulator of various cellular processes such as cell proliferation, migration, and vesicle trafficking.
By targeting PIP5K1B with this antibody, researchers can investigate its function in different cell types and unravel its significance in diseases like cancer, diabetes, and neurological disorders.Understanding the role of PIP5K1B in cellular signaling pathways is essential for developing targeted therapies that manipulate lipid metabolism and membrane dynamics for therapeutic purposes. The PIP5K1B Polyclonal Antibody is a valuable tool for advancing research in this field and uncovering new insights into the molecular mechanisms underlying various pathological conditions.
Product Name:
PIP5K1B Rabbit Polyclonal Antibody
SKU:
CAB7749
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-470 of human PIP5K1B (NP_003549.1).
Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in regulation of phosphatidylinositol 3-kinase signaling. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in uropod.
Purification Method:
Affinity purification
Gene ID:
8395
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PIP5K1B antibody (CAB7749) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
