The Pip5k1a Polyclonal Antibody (CAB7941) is a valuable tool for researchers studying the Pip5k1a protein, which plays a key role in various cellular processes, including cell signaling and membrane trafficking. This antibody, produced in rabbits, is highly specific for Pip5k1a and has been validated for use in Western blot applications.Pip5k1a is a phosphatidylinositol-4-phosphate 5-kinase enzyme that regulates the levels of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), a critical lipid signaling molecule involved in cell signaling pathways.
The ability to detect and analyze Pip5k1a protein levels in different cell types makes this antibody an essential tool for researchers investigating the role of PI(4,5)P2 in cellular functions.Furthermore, understanding the function of Pip5k1a is important for research into various diseases, including cancer, neurological disorders, and immune system dysregulation. By targeting Pip5k1a, researchers can gain insights into potential therapeutic strategies that modulate PI(4,5)P2 levels and signaling pathways associated with disease progression.
Product Name:
PIP5K1A Rabbit Polyclonal Antibody
SKU:
CAB7941
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 231-500 of human PIP5K1A (NP_001129109.1).
Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Located in several cellular components, including lamellipodium; nuclear speck; and ruffle membrane. Colocalizes with mRNA cleavage and polyadenylation specificity factor complex.
Purification Method:
Affinity purification
Gene ID:
8394
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using PIP5K1A antibody (CAB7941) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
