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PIP4K2C Antibody (PACO62767)

SKU:
PACO62767
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • PIP4K2C Antibody PACO62767
  • PIP4K2C Antibody PACO62767
  • PIP4K2C Antibody PACO62767
€359

Description

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PIP4K2C Antibody (PACO62767)

The PIP4K2C Polyclonal Antibody (PAC062767) is a valuable tool for researchers studying PIP4K2C, a protein involved in lipid signaling pathways and cell growth regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards PIP4K2C in human samples, making it ideal for Western blot applications. By binding to the PIP4K2C protein, this antibody enables precise detection and analysis in a variety of cell types, providing valuable insights for studies in cell biology and cancer research.PIP4K2C, also known as phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, is a key player in lipid metabolism and cell proliferation, making it a promising target for therapeutic interventions in cancer and other diseases.

Understanding the functions of PIP4K2C can lead to the development of novel treatments for cancer and other disorders characterized by dysregulated cell growth and signaling pathways. Researchers can leverage the PIP4K2C Polyclonal Antibody to further explore the role of PIP4K2C in cellular processes and disease pathology, paving the way for new therapeutic strategies.

Antibody Name:PIP4K2C Antibody (PACO62767)
Antibody SKU:PACO62767
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Phosphatidylinositol 5-phosphate 4-kinase type-2 γ protein (127-408AA )
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageIHC image of PACO62767 diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product ImageImmunofluorescence staining of U251 cells with PACO62767 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product ImageIHC image of PACO62767 diluted at 1:200 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
Synonyms:Phosphatidylinositol 5-phosphate 4-kinase type-2 γ (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma), PIP4K2C, PIP5K2C
UniProt Protein Function:PIP4K2C: May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Carbohydrate Metabolism - inositol phosphate; Motility/polarity/chemotaxis; EC 2.7.1.149; Endoplasmic reticulum; Kinase, lipid

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: autophagic vacuole; cytosol

Molecular Function:1-phosphatidylinositol-5-phosphate 4-kinase activity; identical protein binding

Biological Process: phosphatidylinositol biosynthetic process; regulation of autophagy; regulation of phosphoinositide 3-kinase cascade

UniProt Code:Q8TBX8
NCBI GenInfo Identifier:317373532
NCBI Gene ID:79837
NCBI Accession:Q8TBX8.3
UniProt Secondary Accession:Q8TBX8,Q9H6N2, B2RDL3, B4DM11, B4DY44,
UniProt Related Accession:Q8TBX8
Molecular Weight:45,053 Da
NCBI Full Name:Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
NCBI Synonym Full Names:phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
NCBI Official Symbol:PIP4K2C  
NCBI Official Synonym Symbols:PIP5K2C  
NCBI Protein Information:phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
UniProt Protein Name:Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
UniProt Synonym Protein Names:Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma
Protein Family:Phosphatidylinositol 5-phosphate 4-kinase
UniProt Gene Name:PIP4K2C  
UniProt Entry Name:PI42C_HUMAN
ELISA Kits
Human PIP4K2C ELISA Kit
Human Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma (PIP4K2C) ELISA Kit
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

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