The Pip4k2b Polyclonal Antibody (CAB12535) is a valuable tool for researchers studying the Pip4k2b protein, which plays a crucial role in cellular signaling pathways associated with lipid metabolism and insulin sensitivity. This antibody, developed by AssayGenie, is generated in rabbits and exhibits high specificity and sensitivity when detecting Pip4k2b in human samples.Pip4k2b has been implicated in the regulation of glucose and lipid metabolism, making it a potential target for therapeutic interventions in metabolic disorders such as diabetes and obesity.
The antibody is validated for use in Western blot applications, allowing for the precise detection and analysis of Pip4k2b levels in various cell types.Researchers in the fields of metabolism, diabetes, and obesity will find the Pip4k2b Polyclonal Antibody to be a valuable tool for their studies. By elucidating the role of Pip4k2b in cellular pathways, this antibody can contribute to a better understanding of metabolic diseases and the development of targeted therapies.
Product Name:
PIP4K2B Rabbit Polyclonal Antibody
SKU:
CAB12535
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PIP4K2B (NP_003550.1).
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
Purification Method:
Affinity purification
Gene ID:
8396
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PIP4K2B antibody (CAB12535) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
