The PINX1 Rabbit Polyclonal Antibody (CAB17172) is a valuable tool for researchers studying the PINX1 protein, a telomere-associated protein involved in regulating telomerase activity and maintaining genomic stability. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications.PINX1 plays a crucial role in telomere maintenance and telomerase regulation, making it a key player in cellular senescence and cancer development. By targeting the PINX1 protein, researchers can gain insights into its function and potential therapeutic implications in cancer treatment and aging-related diseases.
With its high specificity and sensitivity, the PINX1 Rabbit Polyclonal Antibody (CAB17172) is an essential tool for researchers investigating telomere biology, cancer biology, and aging-related mechanisms. Its ability to detect and analyze PINX1 protein expression in various cell types makes it an ideal choice for studies aiming to unravel the complexities of telomere regulation and its impact on human health.
Product Name:
PINX1 Rabbit Polyclonal Antibody
SKU:
CAB17172
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 127-328 of human PINX1 (NP_060354.4).
Enables telomerase RNA binding activity and telomerase inhibitor activity. Involved in several processes, including negative regulation of DNA biosynthetic process; positive regulation of protein localization to nucleolus; and protein localization to organelle. Acts upstream of or within telomere maintenance via telomerase. Located in several cellular components, including chromosomal region; nuclear lumen; and spindle.
Purification Method:
Affinity purification
Gene ID:
54984
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PINX1 Rabbit pAb (CAB17172) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
