The PIN4 Polyclonal Antibody (CAB18173) is specifically designed for research involving PIN4, a protein involved in various cellular processes that play a crucial role in cell growth, differentiation, and apoptosis. This rabbit-raised antibody is highly reactive with human samples and has been validated for use in applications such as Western blotting. PIN4, also known as protein inhibitor of activated STAT 4, is involved in regulating the activity of STAT proteins, which are key players in cellular signaling pathways. By binding to PIN4, this antibody allows for the detection and analysis of PIN4 levels in different cell types, making it an ideal tool for studies in cell biology, oncology, and immunology research.
The importance of PIN4 in mediating cellular responses and pathways underscores its significance as a potential target for therapeutic interventions in diseases such as cancer, where dysregulation of cellular processes can lead to uncontrolled cell growth and proliferation. By further understanding the role of PIN4, researchers can develop novel strategies for targeted therapies and personalized medicine approaches in the treatment of various diseases.
Product Name:
PIN4 Rabbit Polyclonal Antibody
SKU:
CAB18173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-156 of human PIN4 (NP_006214.2).
This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria.
Purification Method:
Affinity purification
Gene ID:
5303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIN4 Rabbit pAb (CAB18173) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
