The PIM3 Polyclonal Antibody (CAB17285) is a valuable tool for researchers studying the PIM3 protein, a member of the PIM family of serine/threonine kinases that play a role in cell survival, proliferation, and differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.PIM3 is known to be involved in the regulation of various cellular processes, including cell cycle progression and apoptosis. Dysregulation of PIM3 has been linked to cancer progression and resistance to therapy, making it an important target for cancer research.
The PIM3 Polyclonal Antibody enables the detection and analysis of PIM3 protein expression in a variety of cell types, providing valuable insights into its function and potential therapeutic strategies.By understanding the role of PIM3 in cancer and other diseases, researchers can develop targeted therapies that exploit the dysregulation of this kinase for more effective treatment options. The PIM3 Polyclonal Antibody is a reliable tool for investigating the biological functions of PIM3 and its implications in disease pathogenesis.
Product Name:
PIM3 Rabbit Polyclonal Antibody
SKU:
CAB17285
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human PIM3 (NP_001001852.2).
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
415116
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIM3 Rabbit pAb (CAB17285) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
