Anti-PIM2 Antibody (CAB9230)
- SKU:
- CAB9230
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Description
Anti-PIM2 Antibody (CAB9230)
The PIM2 Rabbit Monoclonal Antibody (CAB9230) is a valuable tool for researchers studying the PIM2 protein, a member of the PIM family of serine/threonine kinases involved in cell proliferation, survival, and apoptosis. This antibody is highly specific for human samples and is suitable for use in various immunological assays, including Western blot and immunohistochemistry.PIM2 is known to play a role in oncogenesis, with overexpression of the protein linked to tumorigenesis in various cancer types. The ability to accurately detect and analyze PIM2 levels in different cell types makes this antibody essential for cancer research studies aimed at understanding the mechanisms underlying PIM2-mediated tumorigenesis.
By targeting PIM2, researchers can gain insight into the molecular pathways involved in cancer development, potentially leading to the identification of therapeutic targets for the treatment of cancer. The PIM2 Rabbit Monoclonal Antibody is a reliable tool for investigating the role of PIM2 in cancer biology and may serve as a valuable asset in the development of novel cancer therapies.
| Antibody Name: | Anti-PIM2 Antibody |
| Antibody SKU: | CAB9230 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PIM2 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HepG2, K-562, Raji |
| Immunogen: | A synthesized peptide derived from human PIM2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 11040 |
| Uniprot: | Q9P1W9 |
| Cellular Location: | |
| Calculated MW: | 37kDa |
| Observed MW: | 40KDa |
| Synonyms: | |
| Background: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009] |
| UniProt Protein Function: | Pim2: a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. |
| UniProt Protein Details: | Protein type:Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Oncoprotein; EC 2.7.11.1; CAMK group; PIM family Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytoplasm Molecular Function:protein binding; protein serine/threonine kinase activity Biological Process: cell proliferation; G1/S transition of mitotic cell cycle; male meiosis; negative regulation of apoptosis; negative regulation of cell proliferation; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein stabilization; regulation of mitotic cell cycle; response to virus |
| NCBI Summary: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q9P1W9 |
| NCBI GenInfo Identifier: | 20139243 |
| NCBI Gene ID: | 11040 |
| NCBI Accession: | Q9P1W9.1 |
| UniProt Secondary Accession: | Q9P1W9,Q99739, A8K4G6, |
| UniProt Related Accession: | Q9P1W9 |
| Molecular Weight: | 34,190 Da |
| NCBI Full Name: | Serine/threonine-protein kinase pim-2 |
| NCBI Synonym Full Names: | Pim-2 proto-oncogene, serine/threonine kinase |
| NCBI Official Symbol: | PIM2Â Â |
| NCBI Protein Information: | serine/threonine-protein kinase pim-2 |
| UniProt Protein Name: | Serine/threonine-protein kinase pim-2 |
| UniProt Synonym Protein Names: | Pim-2h |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | PIM2Â Â |
| UniProt Entry Name: | PIM2_HUMAN |
 | Western blot - PIM2 Rabbit mAb (CAB9230) |
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