PIM1 Rabbit Polyclonal Antibody (CAB0175)
- SKU:
- CAB0175
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PIM1 Rabbit Polyclonal Antibody |
SKU: | CAB0175 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human PIM1 (NP_002639.1). |
Sequence: | MLLS KINS LAHL RAAP CNDL HATK LAPG KEKE PLES QYQV GPLL GSGG FGSV YSGI RVSD NLPV AIKH VEKD RISD WGEL PNGT RVPM EVVL LKKV SSGF SGVI RLLD WFER PDSF VLIL ERPE PVQD LFDF ITER GALQ EELA RSFF WQVL EAVR HCHN CGVL HRDI KDEN ILID LNRG ELKL IDFG SGAL LKDT VYTD FDGT RVYS PPEW IRYH RYHG RSAA VWSL GILL YDMV CGDI PFEH DEEI IRGQ VFFR QRVS SECQ HLIR WCLA LRPS DRPT FEEI QNHP WMQD VLLP QETA EIHL HSLS PGPS K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PIM; PIM1 |
Positive Sample: | Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 38kDa |
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).
Purification Method: | Affinity purification |
Gene ID: | 5292 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |