The PIK3R3 Polyclonal Antibody (CAB17322) is a valuable tool for researchers studying the PIK3R3 protein, which is an important regulatory subunit of the PI3K complex involved in cell growth, proliferation, and survival pathways. This antibody is produced in rabbits and has been validated for use in Western blot applications, ensuring reliable and specific detection of PIK3R3 in human samples.PIK3R3, also known as p55γ, plays a pivotal role in the PI3K signaling pathway, which is frequently dysregulated in cancer and other diseases. By targeting PIK3R3 with this antibody, researchers can gain insights into its expression levels and function in different cell types, aiding in the study of various biological processes such as cell survival, metabolism, and migration.
The PIK3R3 Polyclonal Antibody is a versatile tool for investigating the role of PIK3R3 in cancer biology, metabolic disorders, and other diseases where PI3K signaling is implicated. Its high reactivity and specificity make it a valuable asset for researchers seeking to unravel the complex mechanisms of PIK3R3 function and its potential as a therapeutic target.
Product Name:
PIK3R3/p55PIK Rabbit Polyclonal Antibody
SKU:
CAB17322
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-388 of human PIK3R3/p55PIK (NP_003620.3).
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity.
Purification Method:
Affinity purification
Gene ID:
8503
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIK3R3/p55PIK Rabbit pAb (CAB17322) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
