The PIK3R2 Polyclonal Antibody (CAB17518) is a valuable tool for researchers studying the PIK3R2 protein, a key regulator of the PI3K signaling pathway. This antibody, produced in rabbits, is highly specific for detecting PIK3R2 in human samples and has been validated for use in Western blot applications.PIK3R2, also known as p85β, is a regulatory subunit of phosphoinositide 3-kinase (PI3K), a signaling pathway involved in cell growth, metabolism, and survival. Dysregulation of PI3K signaling has been implicated in various diseases, including cancer, diabetes, and cardiovascular disorders. By accurately detecting and analyzing PIK3R2 protein levels, researchers can gain insights into the role of PI3K signaling in these diseases and identify potential therapeutic targets.
This PIK3R2 Polyclonal Antibody offers a reliable tool for studying the function and regulation of PIK3R2 in a variety of cell types and tissues. Its high specificity and sensitivity make it suitable for use in immunology, cancer research, and other fields exploring the PI3K signaling pathway. Unlocking the complexities of PIK3R2 protein expression and activity is essential for advancing our understanding of disease mechanisms and developing targeted treatments.
Product Name:
PI3 Kinase p85 beta Rabbit Polyclonal Antibody
SKU:
CAB17518
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 108-298 of human PI3 Kinase p85 beta (NP_005018.1).
Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5296
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PI3 Kinase p85 beta Rabbit pAb (CAB17518) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
