The PIK3R2 Polyclonal Antibody (CAB17433) is specifically designed for research involving PIK3R2, a regulatory subunit of phosphoinositide 3-kinase (PI3K) involved in various cellular processes, including cell growth, proliferation, and survival. The antibody, generated in rabbits, is highly specific to human samples and has been validated for Western blot and immunohistochemistry applications.PIK3R2 plays a crucial role in the PI3K signaling pathway, which is often dysregulated in cancer and other diseases. By targeting PIK3R2 with this antibody, researchers can study the role of this protein in cell signaling pathways, potentially leading to new insights into disease mechanisms and therapeutic targets.
The high sensitivity and specificity of this antibody make it ideal for studies in cancer biology, signal transduction, and drug development.Overall, the PIK3R2 Polyclonal Antibody (CAB17433) is a valuable tool for researchers interested in understanding the role of PIK3R2 in cellular processes and disease pathways. Its versatility in different applications makes it a valuable asset in the fields of cancer research, molecular biology, and drug discovery.
Product Name:
PI3 Kinase p85 beta Rabbit Polyclonal Antibody
SKU:
CAB17433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PI3 Kinase p85 beta (NP_005018.1).
Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5296
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PI3 Kinase p85 beta Rabbit pAb (CAB17433) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
