The PIK3CG Polyclonal Antibody (CAB0266) is specifically designed for research targeting the PIK3CG protein, a key enzyme involved in the PI3K signaling pathway. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PIK3CG protein, this antibody facilitates the detection and analysis of PIK3CG expression in a variety of cell types, making it a valuable tool for studies in cell signaling, metabolism, and cancer biology.PIK3CG, also known as phosphoinositide 3-kinase gamma, plays a crucial role in regulating cell growth, proliferation, and survival.
Dysregulation of the PI3K pathway, often involving aberrant PIK3CG activity, has been implicated in numerous diseases, including cancer, inflammatory disorders, and metabolic syndromes. Investigating the role and function of PIK3CG is essential for gaining insights into disease mechanisms and identifying potential therapeutic targets.By utilizing the PIK3CG Polyclonal Antibody (CAB0266) in your research, you can further elucidate the roles of PIK3CG in cellular processes and disease pathways, paving the way for the development of novel treatments and interventions in various biomedical fields.
Product Name:
PIK3CG Rabbit Polyclonal Antibody
SKU:
CAB0266
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human PIK3CG (NP_002640.2).
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5294
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using PIK3CG Rabbit pAb (CAB0266) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
