The PIK3CD Polyclonal Antibody (CAB16277) is a valuable tool for researchers studying PIK3CD, a key enzyme in the PI3K signaling pathway involved in regulating cell growth, proliferation, and survival. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the PIK3CD protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in immunology, oncology, and other fields exploring PI3K signaling.PIK3CD, also known as phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta, is a crucial player in various cellular processes, including immune responses and cancer development.
Dysregulation of PIK3CD has been implicated in numerous diseases, making it a promising target for therapeutic interventions. Understanding the role of PIK3CD in disease pathology is essential for developing novel treatments that target the PI3K pathway and its downstream effects. By utilizing the PIK3CD Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of PIK3CD in health and disease.
Product Name:
PI3 Kinase p110 delta Rabbit Polyclonal Antibody
SKU:
CAB16277
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-300 of human PI3 Kinase p110 delta (NP_005017.3).
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Purification Method:
Affinity purification
Gene ID:
5293
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse thymus, using PI3 Kinase p110 delta antibody (CAB16277) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
