The PIK3CB Polyclonal Antibody (CAB0982) is a valuable tool for researchers studying the PIK3CB protein, a key regulator of cell growth, proliferation, and survival. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for a variety of research applications, including Western blotting.PIK3CB, also known as phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta, is a crucial component of the PI3K signaling pathway, which is involved in various cellular processes such as cell growth, metabolism, and motility. Dysregulation of PIK3CB has been implicated in numerous diseases, including cancer, diabetes, and cardiovascular disorders, making it an attractive target for drug development and therapeutic interventions.
By using the PIK3CB Polyclonal Antibody, researchers can detect and analyze PIK3CB expression in different cell types, providing valuable insights into its role in disease pathogenesis and potential therapeutic strategies. This antibody is an essential tool for scientists working in the fields of oncology, cell biology, and drug discovery, offering new opportunities for groundbreaking research and advancements in targeted therapy.
Product Name:
PI3 Kinase p110 beta Rabbit Polyclonal Antibody
SKU:
CAB0982
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-600 of human PI3 Kinase p110 beta (NP_006210.1).
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PI3 Kinase p110 beta Rabbit pAb (CAB0982) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
