The PIGU Polyclonal Antibody (CAB18538) is a valuable tool for researchers studying PIGU, a key enzyme involved in the biogenesis of the glycosylphosphatidylinositol (GPI) anchor. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PIGU protein, this antibody enables precise detection and analysis in various cell types, making it an ideal resource for investigations in molecular biology and cell biology.PIGU plays a crucial role in the biosynthesis of GPI anchors, which are essential for anchoring proteins to the cell membrane.
Dysfunction of PIGU has been linked to various diseases, including developmental disorders and neurological conditions. Research on PIGU can provide valuable insights into the mechanisms underlying these diseases and potentially lead to the development of targeted therapies.By using the PIGU Polyclonal Antibody, researchers can further elucidate the function of PIGU in cellular processes and disease pathways, contributing to advancements in biomedicine and potentially paving the way for novel therapeutic strategies.
Product Name:
PIGU Rabbit Polyclonal Antibody
SKU:
CAB18538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PIGU (NP_536724.1).
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins.
Purification Method:
Affinity purification
Gene ID:
128869
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIGU Rabbit pAb (CAB18538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
