The PIGT Polyclonal Antibody (CAB12119) is a valuable tool for researchers studying the PIGT protein, which is involved in the synthesis of glycosylphosphatidylinositol (GPI) anchors. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PIGT protein, this antibody facilitates the detection and analysis of PIGT in a variety of cell types.The PIGT protein plays a crucial role in the biosynthesis of GPI anchors, which are essential for anchoring proteins to the cell membrane. Research into PIGT is particularly relevant in the fields of immunology and cancer, as abnormalities in GPI anchor synthesis have been linked to various diseases.
By studying the function of PIGT, researchers can gain insights into the mechanisms underlying these conditions, paving the way for the development of targeted therapies.Overall, the PIGT Polyclonal Antibody (CAB12119) is a valuable tool for investigating the role of PIGT in cellular processes and disease pathogenesis. Its high reactivity and specificity make it an ideal choice for researchers conducting studies in immunology, cancer biology, and related fields.
Product Name:
PIGT Rabbit Polyclonal Antibody
SKU:
CAB12119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-460 of human PIGT (NP_057021.2).
Endoplasmic reticulum membrane, Single-pass type I membrane protein.
Calculated MW:
66kDa
Observed MW:
66kDa
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
51604
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIGT Rabbit pAb (CAB12119) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
