PIGS Antibody (PACO39362)
- SKU:
- PACO39362
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
PIGS Antibody (PACO39362)
The Pigs Antibody (PAC039362) is a valuable tool for researchers studying immune regulation in pigs. This polyclonal antibody, raised in rabbits, is highly reactive with pig samples and is validated for use in various applications, including Western blot. By binding to the CD300A protein, this antibody enables the detection and analysis of CD300A in pig cells, making it ideal for studies in immunology and cancer research.CD300A, a cell surface molecule known for its immune inhibitory function, plays a crucial role in regulating inflammation and allergic reactions in pigs.
Understanding the role of CD300A in immune response modulation is essential for developing treatments for diseases like cancer, autoimmune disorders, and chronic inflammatory conditions in pigs. The Pigs Antibody (PAC039362) provides researchers with a reliable tool to investigate the function of CD300A in pigs, advancing our understanding of immune regulation in these animals.
| Antibody Name: | PIGS Antibody (PACO39362) |
| Antibody SKU: | PACO39362 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GPI transamidase component PIG-S protein (40-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of HepG2 cells using PACO39362 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. |
| Synonyms: | GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein), PIGS |
| UniProt Protein Function: | PIGS: Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. Belongs to the PIGS family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17p13.2Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membraneMolecular Function: GPI-anchor transamidase activity; protein bindingBiological Process: attachment of GPI anchor to protein |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96S52 |
| NCBI GenInfo Identifier: | 21759353 |
| NCBI Gene ID: | 94005 |
| NCBI Accession: | Q96S52.3 |
| UniProt Secondary Accession: | Q96S52,Q6UVX6 |
| UniProt Related Accession: | Q96S52 |
| Molecular Weight: | 61,005 Da |
| NCBI Full Name: | GPI transamidase component PIG-S |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class S |
| NCBI Official Symbol: | PIGSÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | GPI transamidase component PIG-S |
| UniProt Protein Name: | GPI transamidase component PIG-S |
| UniProt Synonym Protein Names: | Phosphatidylinositol-glycan biosynthesis class S protein |
| Protein Family: | GPI transamidase component |
| UniProt Gene Name: | PIGSÂ Â |
| UniProt Entry Name: | PIGS_HUMAN |
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