PIGR Antibody (PACO28938)
- SKU:
- PACO28938
- Product Type:
- Antibody
- Reactivity:
- Bovine
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PIGR Antibody (PACO28938)
The PIGR Antibody (PAC028938) is a polyclonal antibody specifically designed for research involving the Polymeric Immunoglobulin Receptor (PIGR). The antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various research applications such as Western blotting.The Polymeric Immunoglobulin Receptor (PIGR) is a crucial component of the immune system, playing a key role in the transport of immunoglobulins across mucosal epithelial cells. This process is essential for the passive immunity of newborns and the defense against pathogens at mucosal surfaces. The PIGR Antibody binds specifically to the PIGR protein, allowing for the detection and analysis of this important molecule in different cell types.
Research into the Polymeric Immunoglobulin Receptor (PIGR) has implications in the study of immune responses, mucosal immunity, and the development of therapeutic strategies for infectious diseases and autoimmune conditions. Understanding the function and regulation of PIGR can provide valuable insights into the mechanisms underlying immune protection at mucosal sites and may lead to the development of novel treatments for a range of immune-related disorders.
| Antibody Name: | PIGR Antibody (PACO28938) |
| Antibody SKU: | PACO28938 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Bovine |
| Immunogen: | Recombinant Bovine Polymeric immunoglobulin receptor protein (399-599AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Polymeric immunoglobulin receptor antibody at 2µg/ml + HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 83, 59 kDa Observed band size: 83 kDa . |
| Synonyms: | Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) [Cleaved into: Secretory component], PIGR |
| UniProt Protein Function: | This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P81265 |
| NCBI GenInfo Identifier: | 32189338 |
| NCBI Gene ID: | 281401 |
| NCBI Accession: | NP_776568.1 |
| UniProt Secondary Accession: | P81265 |
| UniProt Related Accession: | P81265 |
| Molecular Weight: | 58,601 Da |
| NCBI Full Name: | polymeric immunoglobulin receptor |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | PIGRÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | polymeric immunoglobulin receptor |
| UniProt Protein Name: | Polymeric immunoglobulin receptor |
| UniProt Synonym Protein Names: | |
| Protein Family: | Polymeric immunoglobulin receptor |
| UniProt Gene Name: | PIGRÂ Â |
| UniProt Entry Name: | PIGR_BOVIN |
Related Products
PIGR Rabbit Polyclonal Antibody (CAB6130)
Human Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit
Bovine Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit
