The PIGQ Polyclonal Antibody (CAB17044) is a valuable tool for research involving PIGQ, a protein involved in the glycosylphosphatidylinositol (GPI) biosynthesis pathway. This antibody, produced in rabbits, is highly specific and reactive with samples from various species, making it versatile for use in a wide range of experimental settings.PIGQ is a crucial enzyme in the GPI biosynthesis pathway, responsible for adding the third mannose residue to the glycan precursor. Defects in this pathway can lead to a range of disorders, including genetic syndromes and neurodegenerative diseases.
By targeting PIGQ with this antibody, researchers can investigate the role of this enzyme in normal physiological processes and disease states.With its validated specificity and sensitivity in techniques such as Western blotting and immunofluorescence, the PIGQ Polyclonal Antibody (CAB17044) is an essential tool for studies in biochemistry, cell biology, and molecular biology. By enabling the detection and analysis of PIGQ in various cell types and tissues, this antibody contributes to advancing our understanding of GPI biosynthesis and its implications in health and disease.
Product Name:
PIGQ Rabbit Polyclonal Antibody
SKU:
CAB17044
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PIGQ (NP_683721.1).
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9091
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIGQ Rabbit pAb (CAB17044) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
