PIDD Rabbit Polyclonal Antibody (CAB4831)
- SKU:
- CAB4831
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PIDD1
- LRDD
- PIDD
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PIDD Rabbit Polyclonal Antibody |
SKU: | CAB4831 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2). |
Sequence: | MAAT VEGP ELEA AAAA GDAS EDSD AGSR ALPF LGGN RLSL DLYP GGCQ QLLH LCVQ QPLQ LLQV EFLR LSTH EDPQ LLEA TLAQ L |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | LRDD; PIDD; MRT75 |
Positive Sample: | U-87MG,293T,K-562,Mouse brain,Mouse liver,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 100kDa |
Observed MW: | 100-110kDa |
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55367 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |