PICK1 Rabbit Polyclonal Antibody (CAB13574)
- SKU:
- CAB13574
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PICK1 Rabbit Polyclonal Antibody |
SKU: | CAB13574 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PICK1 (NP_036539.1). |
Sequence: | CRQE ARAR FSQM RKDV LEKM ELLD QKHV QDIV FQLQ RLVS TMSK YYND CYAV LRDA DVFP IEVD LAHT TLAY GLNQ EEFT DGEE EEEE EDTA AGEP SRDT R |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | PICK; PRKCABP; PICK1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Lipid-anchor, Membrane, Peripheral membrane protein, cytoskeleton, perinuclear region, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome. |
Calculated MW: | 47kDa |
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9463 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |