The PIBF1 Polyclonal Antibody (CAB3072) is a valuable tool for researchers studying PIBF1, a protein known for its role in immune modulation and pregnancy maintenance. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot analyses.PIBF1, also known as progesterone-induced blocking factor 1, is implicated in regulating immune responses during pregnancy and is associated with promoting maternal-fetal tolerance. Its expression has been linked to conditions such as recurrent miscarriage and autoimmune disorders, making it a significant target for further investigation.
By utilizing the PIBF1 Polyclonal Antibody, researchers can accurately detect and analyze PIBF1 expression in various cell types, shedding light on its involvement in immune regulation and reproductive biology. This antibody's reliability and versatility make it a valuable asset in studies related to pregnancy complications, immune disorders, and reproductive health.
Product Name:
PIBF1 Rabbit Polyclonal Antibody
SKU:
CAB3072
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PIBF1 (Q8WXW3).
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma.
Purification Method:
Affinity purification
Gene ID:
10464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using PIBF1 Rabbit pAb (CAB3072) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
