The PIBF1 Polyclonal Antibody (CAB12033) is a valuable tool for research involving PIBF1, a protein associated with immune regulation and pregnancy. This antibody, derived from rabbits, is highly specific for detecting PIBF1 in human samples and is validated for use in various applications, including immunohistochemistry and flow cytometry. By targeting the PIBF1 protein, researchers can investigate its role in immune modulation and its potential impact on reproductive health.PIBF1, also known as progesterone-induced blocking factor 1, is a key player in maintaining immune tolerance during pregnancy, protecting the fetus from rejection by the maternal immune system.
Studies have shown that dysregulation of PIBF1 expression can contribute to complications in pregnancy, making it a promising target for further research in reproductive medicine and immunology. By elucidating the function of PIBF1, scientists can potentially develop new therapies to improve pregnancy outcomes and treat immune-related disorders.
Product Name:
PIBF1 Rabbit Polyclonal Antibody
SKU:
CAB12033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 598-757 of human PIBF1 (NP_006337.2).
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma.
Purification Method:
Affinity purification
Gene ID:
10464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PIBF1 Rabbit pAb (CAB12033) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
