The PIAS4 Polyclonal Antibody (CAB5322) is a valuable tool for researchers studying the function of PIAS4, a protein involved in regulating immune responses and cell signaling pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting PIAS4 in human samples, making it an excellent choice for Western blot experiments.PIAS4, or Protein Inhibitor of Activated STAT4, is a key player in the regulation of gene expression and protein modification, impacting a diverse array of cellular processes. By targeting PIAS4 with this antibody, researchers can gain insights into how this protein influences immune cell function, inflammation, and potentially cancer development.
Investigating the role of PIAS4 is essential for understanding its contribution to disease states and identifying potential therapeutic targets for conditions such as autoimmune disorders and cancer. With the PIAS4 Polyclonal Antibody (CAB5322), scientists can advance their research in immunology and oncology by uncovering new mechanisms of immune regulation and signaling pathways involving PIAS4.
Product Name:
PIAS4 Rabbit Polyclonal Antibody
SKU:
CAB5322
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-260 of human PIAS4 (NP_056981.2).
Enables SUMO ligase activity and ubiquitin protein ligase binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of protein sumoylation; and protein sumoylation. Located in cytoplasm and nucleus.
Purification Method:
Affinity purification
Gene ID:
51588
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PIAS4 Rabbit pAb (CAB5322) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
