PIAS3 Rabbit Polyclonal Antibody (CAB7060)
- SKU:
- CAB7060
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS3 Rabbit Polyclonal Antibody |
SKU: | CAB7060 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-628 of human PIAS3 (NP_006090.2). |
Sequence: | IESS SDEE DLPP TKKH CSVT SAAI PALP GSKG VLTS GHQP SSVL RSPA MGTL GGDF LSSL PLHE YPPA FPLG ADIQ GLDL FSFL QTES QHYG PSVI TSLD EQDA LGHF FQYR GTPS HFLG PLAP TLGS SHCS ATPA PPPG RVSS IVAP GGAL REGH GGPL PSGP SLTG CRSD IISL D |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | ZMIZ5; PIAS3 |
Positive Sample: | 293F,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 68kDa |
Observed MW: | 65-75kDa |
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 10401 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |