PIAS2 Rabbit Monoclonal Antibody (CAB5203)
- SKU:
- CAB5203
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS2 Rabbit Monoclonal Antibody |
SKU: | CAB5203 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PIAS2 (NP_004662.2). |
Sequence: | SPAV QIKI RELY RRRY PRTL EGLS DLST IKSS VFSL DGGS SPVE PDLA VAGI HSLP STSV TPHS PSSP VGSV LLQD TKPT FEMQ QPSP PIPP VHPD VQLK N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | DIP; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIAS2 |
Positive Sample: | Mouse lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle, PML body |
Calculated MW: | 45kDa/6368kDa/68kDa |
Observed MW: | 68kDa |
This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 9063 |
Clone Number: | ARC1256 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |