The PIAS2 Polyclonal Antibody (CAB5654) is a valuable tool for research involving PIAS2, a protein involved in immune regulation and inflammation. This antibody is produced in rabbits and has been validated for use in Western blot applications, enabling detection and analysis of PIAS2 in various cell types.PIAS2, also known as E3 SUMO-protein ligase PIAS2, is a key regulator of immune responses and has been implicated in various diseases including cancer and autoimmune disorders.
By targeting PIAS2, researchers can better understand its role in immune homeostasis and potentially develop new therapeutic strategies for immune-related conditions.With its high reactivity with human samples and specificity for PIAS2 protein, this antibody is an essential tool for studying immune regulation and inflammation in both basic research and clinical applications. Order now to advance your research in immunology and disease biology with the PIAS2 Polyclonal Antibody.
Product Name:
PIAS2 Rabbit Polyclonal Antibody
SKU:
CAB5654
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 420-621 of human PIAS2 (NP_004662.2).
This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
9063
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse testis, using PIAS2 Rabbit pAb (CAB5654) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
