PIAS2 Rabbit Polyclonal Antibody (CAB5654)
- SKU:
- CAB5654
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS2 Rabbit Polyclonal Antibody |
SKU: | CAB5654 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-621 of human PIAS2 (NP_004662.2). |
Sequence: | EDGS WCPM RPKK EAMK VSSQ PCTK IESS SVLS KPCS VTVA SEAS KKKV DVID LTIE SSSD EEED PPAK RKCI FMSE TQSS PTKG VLMY QPSS VRVP SVTS VDPA AIPP SLTD YSVP FHHT PISS MSSD LPGL DFLS LIPV DPQY CPPM FLDS LTSP LTAS STSV TTTS SHES STHV SSSS SRSE TGVI TSSG SNIP DIIS LD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | DIP; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIAS2 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle, PML body. |
Calculated MW: | 68kDa |
Observed MW: | 75kDa |
This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 9063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |