PIAS1 Rabbit Polyclonal Antibody (CAB5729)
- SKU:
- CAB5729
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS1 Rabbit Polyclonal Antibody |
SKU: | CAB5729 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 422-651 of human PIAS1 (NP_057250.1). |
Sequence: | VQEV SASY NGVD GCLS STLE HQVA SHHQ SSNK NKKV EVID LTID SSSD EEEE EPSA KRTC PSLS PTSP LNNK GILS LPHQ ASPV SRTP SLPA VDTS YINT SLIQ DYRH PFHM TPMP YDLQ GLDF FPFL SGDN QHYN TSLL AAAA AAVS DDQD LLHS SRFF PYTS SQMF LDQL SAGG STSL PTTN GSSS GSNS SLVS SNSL RESH SHTV TNRS STDT ASIF GIIP DIIS LD |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | GBP; ZMIZ3; DDXBP1; GU/RH-II; PIAS1 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle, PML body. |
Calculated MW: | 72kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8554 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |