PIAS1 Rabbit Polyclonal Antibody (CAB1007)
- SKU:
- CAB1007
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PIAS1 Rabbit Polyclonal Antibody |
SKU: | CAB1007 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human PIAS1 (NP_057250.1). |
Sequence: | MADS AELK QMVM SLRV SELQ VLLG YAGR NKHG RKHE LLTK ALHL LKAG CSPA VQMK IKEL YRRR FPQK IMTP ADLS IPNV HSSP MPAT LSPS TIPQ LTYD GHPA SSPL LPVS LLGP KHEL ELPH LTSA LHPV HPDI KLQK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GBP; ZMIZ3; DDXBP1; GU/RH-II; PIAS1 |
Positive Sample: | HeLa,Jurkat,Raji,Mouse brain,Mouse kidney,Rat testis,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle, PML body. |
Calculated MW: | 72kDa |
Observed MW: | 76kDa |
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8554 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |