The Elafin Polyclonal Antibody (CAB5441) is a valuable tool for researchers studying Elafin, a serine protease inhibitor involved in immune regulation and inflammation. This antibody is produced in rabbits and shows high reactivity with human samples, making it suitable for use in Western blot applications. By targeting the Elafin protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in immunology and inflammatory diseases.
Elafin, also known as an anti-inflammatory molecule, plays a crucial role in maintaining immune homeostasis by regulating inflammatory responses. Its involvement in modulating inflammation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of Elafin is key to developing targeted therapies that can modulate immune responses in these disease contexts.
Product Name:
PI3 Rabbit Polyclonal Antibody
SKU:
CAB5441
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-117 of human PI3 (NP_002629.1).
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
Purification Method:
Affinity purification
Gene ID:
5266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PI3 Rabbit pAb (CAB5441) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
