The PI3 Kinase p110 Beta Monoclonal Antibody (CAB22467) is a valuable tool for researchers studying the PI3 Kinase signaling pathway, specifically targeting the p110 Beta isoform. This antibody, produced by AssayGenie, is monoclonal in nature, ensuring high specificity and sensitivity in experimental applications.The PI3 Kinase p110 Beta Monoclonal Antibody has been validated for use in various research applications, including Western blotting, immunoprecipitation, and immunofluorescence. It binds specifically to the p110 Beta subunit of PI3 Kinase, enabling researchers to detect and analyze protein expression levels in different cell types and tissues.The PI3 Kinase signaling pathway is known to play a crucial role in various cellular processes, including cell growth, proliferation, and survival.
Dysregulation of this pathway has been implicated in numerous diseases, including cancer, diabetes, and cardiovascular disorders. By using the PI3 Kinase p110 Beta Monoclonal Antibody, researchers can gain insights into the activation and regulation of this important pathway, ultimately helping to develop targeted therapies for diseases associated with PI3 Kinase dysfunction.Overall, the PI3 Kinase p110 Beta Monoclonal Antibody is a reliable tool for researchers interested in studying the PI3 Kinase signaling pathway and its implications in disease. Its high specificity and versatility make it a valuable asset in the fields of cancer research, immunology, and
Product Name:
PI3 Kinase p110 beta Monoclonal Antibody
SKU:
CAB22467
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-600 of human PI3 Kinase p110 beta (NP_006210.1).
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5291
Clone Number:
ARC54484
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PI3 Kinase p110 beta Rabbit mAb (CAB22467) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
